Publications

2022

A spatio-temporally constrained gene regulatory network directed by PBX1/2 acquires limb patterning specificity via HAND2
Marta Losa, Iros Barozzi, Marco Osterwalder, Peyman Zarrineh, Jean Denis Benazet, Brandon Chacon, Ausra Girdziusaite, Angela Morabito, Jianjian Zhu, Susan Mackem, Terence D. Capellini, Nicoletta Bobola, Diane Dickel, Aimee Zuniga, Axel Visel, Rolf Zeller, Licia Selleri    bioRxiv 2022.03.08.483529; doi: https://doi.org/10.1101/2022.03.08.483529

2021

Loss of Extreme Long-Range Enhancers in Human Neural Crest Drives a Craniofacial Disorder
Hannah K. Long, Marco Osterwalder, Ian C. Welsh, Karissa Hansen, James O.J. Davies, Yiran E. Liu, Mervenaz Koska, Alexander T. Adams, Robert Aho, Neha Arora, Kazuya Ikeda, Ruth M. Williams, Tatjana Sauka-Spengler, Matthew H. Porteus, Tim Mohun, Diane E. Dickel, Tomek Swigut, Jim R. Hughes, Douglas R. Higgs, Axel Visel, Licia Selleri, Joanna Wysocka Cell Stem Cell. 2020 Nov 5; 27(5): 765–783.e14. doi: 10.1016/j.stem.2020.09.001 PMCID: PMC7655526

FaceBase 3: analytical tools and FAIR resources for craniofacial and dental research
Bridget D. Samuels, Robert Aho, James F. Brinkley, Alejandro Bugacov, Eleanor Feingold, Shannon Fisher, Ana S. Gonzalez-Reiche, Joseph G. Hacia, Benedikt Hallgrimsson, Karissa Hansen, Matthew P. Harris, Thach-Vu Ho, Greg Holmes, Joan E. Hooper, Ethylin Wang Jabs, Kenneth L. Jones, Carl Kesselman, Ophir D. Klein, Elizabeth J. Leslie, Hong Li, Eric C. Liao, Hannah Long, Na Lu, Richard L. Maas, Mary L. Marazita, Jaaved Mohammed, Sara Prescott, Robert Schuler, Licia Selleri, Richard A. Spritz, Tomek Swigut, Harm van Bakel, Axel Visel, Ian Welsh, Cristina Williams, Trevor J. Williams, Joanna Wysocka, Yuan Yuan, Yang Chai Development. 2020 Sep 15; 147(18): dev191213. Published online 2020 Sep 23. doi: 10.1242/dev.191213 PMCID: PMC7522026

A specialized niche in the pancreatic microenvironment promotes endocrine differentiation
Corinna Cozzitorto, Laura Mueller, Silvia Ruzittu, Nancy Mah, David Willnow, Jean-Francois Darrigrand, Heather Wilson, Daniel Khosravinia, Amir-Ala Mahmoud, Maurizio Risolino, Licia Selleri, Francesca M. Spagnoli Dev Cell. Author manuscript; available in PMC 2021 Oct 26.Published in final edited form as: Dev Cell. 2020 Oct 26; 55(2): 150–162.e6. Published online 2020 Aug 27. doi: 10.1016/j.devcel.2020.08.003 PMCID: PMC7720791

Functional characterization of a novel PBX1 de novo missense variant identified in a patient with syndromic congenital heart disease
Dimuthu Alankarage, Justin O Szot, Nick Pachter, Anne Slavotinek, Licia Selleri, Joseph T Shieh, David Winlaw, Eleni Giannoulatou, Gavin Chapman, Sally L Dunwoodie Hum Mol Genet. 2020 May 8; 29(7): 1068–1082. Published online 2019 Oct 18. doi: 10.1093/hmg/ddz231 PMCID: PMC7206850

2019

'Building a perfect body': control of vertebrate organogenesis by PBX-dependent regulatory networks
Licia Selleri, Vincenzo Zappavigna, Elisabetta Ferretti Genes Dev. 2019 Mar 1; 33(5-6): 258–275. doi: 10.1101/gad.318774.118 PMCID: PMC6411007

Genetics of scapula and pelvis development: An evolutionary perspective
Mariel Young, Licia Selleri, Terence D. Capellini Curr Top Dev Biol. Author manuscript; available in PMC 2019 Mar 22.Published in final edited form as: Curr Top Dev Biol. 2019; 132: 311–349. Published online 2019 Jan 7. doi: 10.1016/bs.ctdb.2018.12.007 PMCID: PMC6430119

2018

Incomplete penetrance for isolated congenital asplenia in humans with mutations in translated and untranslated RPSA exons
Alexandre Bolze, Bertrand Boisson, Barbara Bosch, Alexander Antipenko, Matthieu Bouaziz, Paul Sackstein, Malik Chaker-Margot, Vincent Barlogis, Tracy Briggs, Elena Colino, Aurora C. Elmore, Alain Fischer, Ferah Genel, Angela Hewlett, Maher Jedidi, Jadranka Kelecic, Renate Krüger, Cheng-Lung Ku, Dinakantha Kumararatne, Alain Lefevre-Utile, Sam Loughlin, Nizar Mahlaoui, Susanne Markus, Juan-Miguel Garcia, Mathilde Nizon, Matias Oleastro, Malgorzata Pac, Capucine Picard, Andrew J. Pollard, Carlos Rodriguez-Gallego, Caroline Thomas, Horst Von Bernuth, Austen Worth, Isabelle Meyts, Maurizio Risolino, Licia Selleri, Anne Puel, Sebastian Klinge, Laurent Abel, Jean-Laurent Casanova Proc Natl Acad Sci U S A. 2018 Aug 21; 115(34): E8007–E8016. Published online 2018 Aug 2. doi: 10.1073/pnas.1805437115 PMCID: PMC6112730

Pbx loss in cranial neural crest, unlike in epithelium, results in cleft palate only and a broader midface
Ian C. Welsh, James Hart, Joel M. Brown, Karissa Hansen, Marcelo Rocha Marques, Robert J. Aho, Irina Grishina, Romulo Hurtado, Doris Herzlinger, Elisabetta Ferretti, Maria J. Garcia‐Garcia, Licia Selleri J Anat. 2018 Aug; 233(2): 222–242. Published online 2018 May 23. doi: 10.1111/joa.12821 PMCID: PMC6036936

Face morphogenesis is promoted by Pbx-dependent EMT via regulation of Snail1 during frontonasal prominence fusion
Marta Losa, Maurizio Risolino, Bingsi Li, James Hart, Laura Quintana, Irina Grishina, Hui Yang, Irene F. Choi, Patrick Lewicki, Sameer Khan, Robert Aho, Jennifer Feenstra, C. Theresa Vincent, Anthony M. C. Brown, Elisabetta Ferretti, Trevor Williams, Licia Selleri Development. 2018 Mar 1; 145(5): dev157628. doi: 10.1242/dev.157628 PMCID: PMC5868993

PBX transcription factors drive pulmonary vascular adaptation to birth
David J. McCulley, Mark D. Wienhold, Elizabeth A. Hines, Timothy A. Hacker, Allison Rogers, Ryan J. Pewowaruk, Rediet Zewdu, Naomi C. Chesler, Licia Selleri, Xin Sun J Clin Invest. 2018 Feb 1; 128(2): 655–667. Published online 2017 Dec 18. doi: 10.1172/JCI93395 PMCID: PMC5785269

2017

De novo, deleterious sequence variants that alter the transcriptional activity of the homeoprotein PBX1 are associated with intellectual disability and pleiotropic developmental defects
Anne Slavotinek, Maurizio Risolino, Marta Losa, Megan T Cho, Kristin G Monaghan, Dina Schneidman-Duhovny, Sarah Parisotto, Johanna C Herkert, Alexander P A Stegmann, Kathryn Miller, Natasha Shur, Jacqueline Chui, Eric Muller, Suzanne DeBrosse, Justin O Szot, Gavin Chapman, Nicholas S Pachter, David S Winlaw, Bryce A Mendelsohn, Joline Dalton, Kyriakie Sarafoglou, Peter I Karachunski, Jane M Lewis, Helio Pedro, Sally L Dunwoodie, Licia Selleri, Joseph Shieh Hum Mol Genet. 2017 Dec 15; 26(24): 4849–4860. Published online 2017 Sep 22. doi: 10.1093/hmg/ddx363 PMCID: PMC6455034

Towards Microsurgical Correction of Cleft Lip Ex Utero via Restoration of Craniofacial Developmental Programs
Xue Dong, Wilmina N. Landford, James Hart, Maurizio Risolino, Omer Kaymakcalan, Julia Jin, Yoshiko Toyoda, Elisabetta Ferretti, Licia Selleri, Jason A. Spector Plast Reconstr Surg. Author manuscript; available in PMC 2018 Jul 1.Published in final edited form as: Plast Reconstr Surg. 2017 Jul; 140(1): 75–85. doi: 10.1097/PRS.0000000000003417 PMCID: PMC5886781

2016

A Hox-Embedded Long Noncoding RNA: Is It All Hot Air?
Licia Selleri, Marisa S. Bartolomei, Wendy A. Bickmore, Lin He, Lisa Stubbs, Wolf Reik, Gregory S. Barsh PLoS Genet. 2016 Dec; 12(12): e1006485. Published online 2016 Dec 15. doi:& 10.1371/journal.pgen.1006485 PMCID: PMC5157941

Ovarian cancer chemoresistance relies on the the stem cell reprogramming factor PBX1
Jin-Gyoung Jung, Ie-Ming Shih, Joon Tae Park, Emily Gerry, Tae Hoen Kim, Ayse Ayhan, Karen Handschuh, Ben Davidson, Amanda Nickles Fader, Licia Selleri, Tian-Li Wang Cancer Res. Author manuscript; available in PMC 2020 Jul 22.Published in final edited form as: Cancer Res. 2016 Nov 1; 76(21): 6351–6361. Published online 2016 Sep 2. doi: 10.1158/0008-5472.CAN-16-0980 PMCID: PMC7375390

Parallel Pbx-Dependent Pathways Govern the Coalescence and Fate of Motor Columns
Olivia Hanley, Rediet Zewdu, Lisa J. Cohen, Heekyung Jung, Julie Lacombe, Polyxeni Philippidou, David H. Lee, Licia Selleri, Jeremy S. Dasen Neuron. Author manuscript; available in PMC 2017 Sep 7.Published in final edited form as: Neuron. 2016 Sep 7; 91(5): 1005–1020. Published online 2016 Aug 25. doi: 10.1016/j.neuron.2016.07.043 PMCID: PMC5017921

The FaceBase Consortium: a comprehensive resource for craniofacial researchers
James F. Brinkley, Shannon Fisher, Matthew P. Harris, Greg Holmes, Joan E. Hooper, Ethylin Wang Jabs, Kenneth L. Jones, Carl Kesselman, Ophir D. Klein, Richard L. Maas, Mary L. Marazita, Licia Selleri, Richard A. Spritz, Harm van Bakel, Axel Visel, Trevor J. Williams, Joanna Wysocka, FaceBase Consortium, Yang Chai Development. 2016 Jul 15; 143(14): 2677–2688. doi: 10.1242/dev.135434 PMCID: PMC4958338

Pbx1 is required for adult subventricular zone neurogenesis
Britta Moyo Grebbin, Ann-Christin Hau, Anja Groß, Marie Anders-Maurer, Jasmine Schramm, Matthew Koss, Christoph Wille, Michel Mittelbronn, Licia Selleri, Dorothea Schulte Development. 2016 Jul 1; 143(13): 2281–2291. doi: 10.1242/dev.128033 PMCID: PMC4958316

A PBX1 transcriptional network controls dopaminergic neuron development and is impaired in Parkinson's disease
J Carlos Villaescusa, Bingsi Li, Enrique M Toledo, Pia Rivetti di Val Cervo, Shanzheng Yang, Simon RW Stott, Karol Kaiser, Saiful Islam, Daniel Gyllborg, Rocio Laguna‐Goya, Michael Landreh, Peter Lönnerberg, Anna Falk, Tomas Bergman, Roger A Barker, Sten Linnarsson, Licia Selleri, Ernest Arenas EMBO J. 2016 Sep 15; 35(18): 1963–1978. Published online 2016 Jun 28. doi: 10.15252/embj.201593725 PMCID: PMC5282836

Spleen hypoplasia leads to abnormal stress hematopoiesis in mice with loss of Pbx homeoproteins in splenic mesenchyme
Rediet Zewdu, Maurizio Risolino, Alexandru Barbulescu, Pradeep Ramalingam, Jason M. Butler, Licia Selleri J Anat. 2016 Jul; 229(1): 153–169. Published online 2016 Apr 14. doi: 10.1111/joa.12479 PMCID: PMC5341595

2015

Pbx regulates patterning of the cerebral cortex in progenitors and postmitotic neurons
Olga Golonzhka, Alex Nord, Paul LF Tang, Susan Lindtner, Athena R Ypsilanti, Elisabetta Ferretti, Axel Visel, Licia Selleri, John L.R. Rubenstein Neuron. Author manuscript; available in PMC 2016 Dec 16. Published in final edited form as: Neuron. 2015 Dec 16; 88(6): 1192–1207. Published online 2015 Dec 6. doi: 10.1016/j.neuron.2015.10.045 PMCID: PMC4688141

Enhancer divergence and cis-regulatory evolution in the human and chimp neural crest
Sara L. Prescott, Rajini Srinivasan, Maria Carolina Marchetto, Irina Grishina, Iñigo Narvaiza, Licia Selleri, Fred H. Gage, Tomek Swigut, Joanna Wysocka Cell. Author manuscript; available in PMC 2016 Sep 24. Published in final edited form as: Cell. 2015 Sep 24; 163(1): 68–83. Published online 2015 Sep 10. doi: 10.1016/j.cell.2015.08.036 PMCID: PMC4848043

Pbx1-dependent control of VMC differentiation kinetics underlies gross renal vascular patterning
Romulo Hurtado, Rediet Zewdu, James Mtui, Cindy Liang, Robert Aho, Chad Kurylo, Licia Selleri, Doris Herzlinger Development. 2015 Aug 1; 142(15): 2653–2664. doi: 10.1242/dev.124776 PMCID: PMC4529034

An allelic series of miR-17~92 mutant mice uncovers functional specialization and cooperation among members of a miRNA polycistron
Yoon-Chi Han, Joana A. Vidigal, Ping Mu, Evelyn Yao, Irtisha Singh, Alvaro J. González, Carla P. Concepcion, Ciro Bonetti, Paul Ogrodowski, Brett Carver, Licia Selleri, Doron Betel, Christina Leslie, Andrea Ventura Nat Genet. Author manuscript; available in PMC 2016 Jan 1.Published in final edited form as: Nat Genet. 2015 Jul; 47(7): 766–775. Published online 2015 Jun 1. doi: 10.1038/ng.3321 PMCID: PMC4485521

2014

Mouse regulatory DNA landscapes reveal global principles of cis-regulatory evolution
Jeff Vierstra, Eric Rynes, Richard Sandstrom, Miaohua Zhang, Theresa Canfield, R. Scott Hansen, Sandra Stehling-Sun, Peter J. Sabo, Rachel Byron, Richard Humbert, Robert E. Thurman, Audra K. Johnson, Shinny Vong, Kristen Lee, Daniel Bates, Fidencio Neri, Morgan Diegel, Erika Giste, Eric Haugen, Douglas Dunn, Matthew S. Wilken, Steven Josefowicz, Robert Samstein, Kai-Hsin Chang, Evan E. Eichler, Marella De Bruijn, Thomas A. Reh, Arthur Skoultchi, Alexander Rudensky, Stuart H. Orkin, Thalia Papayannopoulou, Piper M. Treuting, Licia Selleri, Rajinder Kaul, Mark Groudine, M. A. Bender, John A. Stamatoyannopoulos Science 2014 Nov 21; 346(6212): 1007–1012. doi: 10.1126/science.1246426 PMCID: PMC4337786

A comparative encyclopedia of DNA elements in the mouse genome
Feng Yue, Yong Cheng, Alessandra Breschi, Jeff Vierstra, Weisheng Wu, Tyrone Ryba, Richard Sandstrom, Zhihai Ma, Carrie Davis, Benjamin D. Pope, Yin Shen, Dmitri D. Pervouchine, Sarah Djebali, Robert E. Thurman, Rajinder Kaul, Eric Rynes, Anthony Kirilusha, Georgi K. Marinov, Brian A. Williams, Diane Trout, Henry Amrhein, Katherine Fisher-Aylor, Igor Antoshechkin, Gilberto DeSalvo, Lei-Hoon See, Meagan Fastuca, Jorg Drenkow, Chris Zaleski, Alex Dobin, Pablo Prieto, Julien Lagarde, Giovanni Bussotti, Andrea Tanzer, Olgert Denas, Kanwei Li, M. A. Bender, Miaohua Zhang, Rachel Byron, Mark T. Groudine, David McCleary, Long Pham, Zhen Ye, Samantha Kuan, Lee Edsall, Yi-Chieh Wu, Matthew D. Rasmussen, Mukul S. Bansal, Manolis Kellis, Cheryl A. Keller, Christapher S. Morrissey, Tejaswini Mishra, Deepti Jain, Nergiz Dogan, Robert S. Harris, Philip Cayting, Trupti Kawli, Alan P. Boyle, Ghia Euskirchen, Anshul Kundaje, Shin Lin, Yiing Lin, Camden Jansen, Venkat S. Malladi, Melissa S. Cline, Drew T. Erickson, Vanessa M. Kirkup, Katrina Learned, Cricket A. Sloan, Kate R. Rosenbloom, Beatriz Lacerda de Sousa, Kathryn Beal, Miguel Pignatelli, Paul Flicek, Jin Lian, Tamer Kahveci, Dongwon Lee, W. James Kent, Miguel Ramalho Santos, Javier Herrero, Cedric Notredame, Audra Johnson, Shinny Vong, Kristen Lee, Daniel Bates, Fidencio Neri, Morgan Diegel, Theresa Canfield, Peter J. Sabo, Matthew S. Wilken, Thomas A. Reh, Erika Giste, Anthony Shafer, Tanya Kutyavin, Eric Haugen, Douglas Dunn, Alex P. Reynolds, Shane Neph, Richard Humbert, R. Scott Hansen, Marella De Bruijn, Licia Selleri, Alexander Rudensky, Steven Josefowicz, Robert Samstein, Evan E. Eichler, Stuart H. Orkin, Dana Levasseur, Thalia Papayannopoulou, Kai-Hsin Chang, Arthur Skoultchi, Srikanta Gosh, Christine Disteche, Piper Treuting, Yanli Wang, Mitchell J. Weiss, Gerd A. Blobel, Xiaoyi Cao, Sheng Zhong, Ting Wang, Peter J. Good, Rebecca F. Lowdon, Leslie B. Adams, Xiao-Qiao Zhou, Michael J. Pazin, Elise A. Feingold, Barbara Wold, James Taylor, Ali Mortazavi, Sherman M. Weissman, John A. Stamatoyannopoulos, Michael P. Snyder, Roderic Guigo, Thomas R. Gingeras, David M. Gilbert, Ross C. Hardison, Michael A. Beer, Bing Ren, The Mouse ENCODE Consortium Nature. 2014; 515(7527): 355–364. 10.1038/nature13992 PMCID: PMC4266106

A comparative encyclopedia of DNA elements in the mouse genome.
Yue F, Cheng Y, Breschi A, Vierstra J, Wu W, Ryba T, Sandstrom R, Ma Z, Davis C, Pope BD, Shen Y, Pervouchine DD, Djebali S, Thurman RE, Kaul R, Rynes E, Kirilusha A, Marinov GK, Williams BA, Trout D, Amrhein H, Fisher-Aylor K, Antoshechkin I, DeSalvo G, See LH, Fastuca M, Drenkow J, Zaleski C, Dobin A, Prieto P, Lagarde J, Bussotti G, Tanzer A, Denas O, Li K, Bender MA, Zhang M, Byron R, Groudine MT, McCleary D, Pham L, Ye Z, Kuan S, Edsall L, Wu YC, Rasmussen MD, Bansal MS, Kellis M, Keller CA, Morrissey CS, Mishra T, Jain D, Dogan N, Harris RS, Cayting P, Kawli T, Boyle AP, Euskirchen G, Kundaje A, Lin S, Lin Y, Jansen C, Malladi VS, Cline MS, Erickson DT, Kirkup VM, Learned K, Sloan CA, Rosenbloom KR, Lacerda de Sousa B, Beal K, Pignatelli M, Flicek P, Lian J, Kahveci T, Lee D, Kent WJ, Ramalho Santos M, Herrero J, Notredame C, Johnson A, Vong S, Lee K, Bates D, Neri F, Diegel M, Canfield T, Sabo PJ, Wilken MS, Reh TA, Giste E, Shafer A, Kutyavin T, Haugen E, Dunn D, Reynolds AP, Neph S, Humbert R, Hansen RS, De Bruijn M, Selleri L, Rudensky A, Josefowicz S, Samstein R, Eichler EE, Orkin SH, Levasseur D, Papayannopoulou T, Chang KH, Skoultchi A, Gosh S, Disteche C, Treuting P, Wang Y, Weiss MJ, Blobel GA, Cao X, Zhong S, Wang T, Good PJ, Lowdon RF, Adams LB, Zhou XQ, Pazin MJ, Feingold EA, Wold B, Taylor J, Mortazavi A, Weissman SM, Stamatoyannopoulos JA, Snyder MP, Guigo R, Gingeras TR, Gilbert DM, Hardison RC, Beer MA, Ren B; Mouse ENCODE Consortium. Nature. 2014 Nov 20;515(7527):355-64. doi: 10.1038/nature13992. PMID: 25409824; PMCID: PMC4266106

ESCRT-II/Vps25 constrains digit number by endosome-mediated selective modulation of FGF-SHH signaling
Karen Handschuh, Jennifer Feenstra, Matthew Koss, Elisabetta Ferretti, Maurizio Risolino, Rediet Zewdu, Michelle A. Sahai, Jean-Denis Bénazet, Xiao P. Peng, Michael J. Depew, Laura Quintana, James Sharpe, Baolin Wang, Heather Alcorn, Roberta Rivi, Stephen Butcher, J Robert Manak, Thomas Vaccari, Harel Weinstein, Kathryn V. Anderson, Elizabeth Lacy, Licia Selleri Cell Rep. Cell Rep. 2014 Oct 23; 9(2): 674–687. Published online 2014 Oct 16. doi: 10.1016/j.celrep.2014.09.019 PMCID: PMC4223648

2013

ADAM17 Controls Endochondral Ossification by Regulating Terminal Differentiation of Chondrocytes Katherine C. Hall, Daniel Hill, Miguel Otero, Darren A. Plumb, Dara Froemel, Cecilia L. Dragomir, Thorsten Maretzky, Adele Boskey, Howard C. Crawford, Licia Selleri, Mary B. Goldring, Carl P. Blobel Mol Cell Biol. 2013 Aug; 33(16): 3077–3090. doi: 10.1128/MCB.00291-13 PMCID: PMC3753912

Ribosomal protein SA haploinsufficiency in humans with isolated congenital asplenia
Alexandre Bolze, Nizar Mahlaoui, Minji Byun, Bridget Turner, Nikolaus Trede, Steven R. Ellis, Avinash Abhyankar, Yuval Itan, Etienne Patin, Samuel Brebner, Paul Sackstein, Anne Puel, Capucine Picard, Laurent Abel, Lluis Quintana-Murci, Saul N. Faust, Anthony P. Williams, Richard Baretto, Michael Duddridge, Usha Kini, Andrew J. Pollard, Catherine Gaud, Pierre Frange, Daniel Orbach, Jean-Francois Emile, Jean-Louis Stephan, Ricardo Sorensen, Alessandro Plebani, Lennart Hammarstrom, Mary Ellen Conley, Licia Selleri, Jean-Laurent Casanova Science. Author manuscript; available in PMC 2013 Jun 10.Published in final edited form as: Science. 2013 May 24; 340(6135): 976–978. Published online 2013 Apr 11. doi: 10.1126/science.1234864 PMCID: PMC3677541

2012

The hSSB1 orthologue Obfc2b is essential for skeletogenesis but dispensable for the DNA damage response in vivo
Niklas Feldhahn, Elisabetta Ferretti, Davide F Robbiani, Elsa Callen, Stephanie Deroubaix, Licia Selleri, Andre Nussenzweig, Michel C Nussenzweig EMBO J. 2012 Oct 17; 31(20): 4045–4056. Published online 2012 Aug 31. doi: 10.1038/emboj.2012.247

Congenital Asplenia in Mice and Humans with Mutations in a Pbx/Nkx2-5/p15 Module
Matthew Koss, Alexandre Bolze, Andrea Brendolan, Matilde Saggese, Terence D. Capellini, Ekaterina Bojilova, Bertrand Boisson, Owen W.J. Prall, David Elliott, Mark Solloway, Elisa Lenti, Chisa Hidaka, Ching-Pin Chang, Nizar Mahlaoui, Richard P. Harvey, Jean-Laurent Casanova, Licia Selleri Dev Cell. Author manuscript; available in PMC 2013 May 15.Published in final edited form as: Dev Cell. 2012 May 15; 22(5): 913–926. Published online 2012 May 3. doi: 10.1016/j.devcel.2012.02.009 PMCID: PMC3356505

2011

A Conserved Pbx-Wnt-p63-Irf6 Regulatory Module Controls Face Morphogenesis by Promoting Epithelial Apoptosis
Elisabetta Ferretti, Bingsi Li, Rediet Zewdu, Victoria Wells, Jean M. Hebert, Courtney Karner, Matthew J. Anderson, Trevor Williams, Jill Dixon, Michael J. Dixon, Michael J. Depew, Licia Selleri Dev Cell. Author manuscript; available in PMC 2012 Oct 18.Published in final edited form as: Dev Cell. 2011 Oct 18; 21(4): 627–641. Published online 2011 Oct 6. doi: 10.1016/j.devcel.2011.08.005 PMCID: PMC3199312

Epigenetic Regulation of Early Osteogenesis and Mineralized Tissue Formation by a HOXA10-PBX1-Associated Complex
Jonathan A.R. Gordon, Mohammad Q. Hassan, Matthew Koss, Martin Montecino, Licia Selleri, Andre J. van Wijnen, Janet L. Stein, Gary S. Stein, Jane B. Lian Cells Tissues Organs. 2011 Aug; 194(2-4): 146–150. ;Published online 2011 May 19. doi: 10.1159/000324790 PMCID: PMC3178072

Hox and Pbx Factors Control Retinoic Acid Synthesis during Hindbrain Segmentation
Antonio Vitobello, Elisabetta Ferretti, Xavier Lampe, Nathalie Vilain, Sebastien Ducret, Michela Ori, Jean-François Spetz, Licia Selleri, Filippo M. Rijli Dev Cell. Author manuscript; available in PMC 2013 Jun 10. Published in final edited form as: Dev Cell. 2011 Apr 19; 20(4): 469–482. doi: 10.1016/j.devcel.2011.03.011 PMCID: PMC3677862

Control of Pelvic Girdle Development by Genes of the Pbx Family and Emx2
Terence D. Capellini, Karen Handschuh, Laura Quintana, Elisabetta Ferretti, Giuseppina Di Giacomo, Sebastian Fantini, Giulia Vaccari, Shoa L. Clarke, Aaron M. Wenger, Gill Bejerano, James Sharpe, Vincenzo Zappavigna, Licia Selleri Dev Dyn. Author manuscript; available in PMC 2012 May 1.Published in final edited form as: Dev Dyn. 2011 May; 240(5): 1173–1189. Published online 2011 Mar 31. doi: 10.1002/dvdy.22617 PMCID: PMC3081414

Pbx Homeodomain Proteins: TALEnted regulators of Limb Patterning and Outgrowth
Terence D. Capellini, Vincenzo Zappavigna, Licia Selleri Dev Dyn. Author manuscript; available in PMC 2012 May 1. Published in final edited form as: Dev Dyn. 2011 May; 240(5): 1063–1086. Published online 2011 Mar 17. doi: 10.1002/dvdy.22605 PMCID: PMC3081394

2010 and earlier

Scapula development is governed by genetic interactions of Pbx1 with its family members and with Emx2 via their cooperative control of Alx1
Terence D. Capellini, Giulia Vaccari, Elisabetta Ferretti, Sebastian Fantini, Mu He, Massimo Pellegrini, Laura Quintana, Giuseppina Di Giacomo, James Sharpe, Licia Selleri, Vincenzo Zappavigna Development. 2010 Aug 1; 137(15): 2559–2569. doi: 10.1242/dev.048819 PMCID: PMC2927673

Conservation of Notochord Gene Expression Across Chordates: Insights From the Leprecan Gene Family
Terence D. Capellini, Matthew P. Dunn, Yale J. Passamaneck, Licia Selleri, Anna Di Gregorio Genesis. Author manuscript; available in PMC 2011 Mar 28. Published in final edited form as: Genesis. 2008 Nov; 46(11): 683–696. doi: 10.1002/dvg.20406 PMCID: PMC3065379

Pbx/Meis Deficiencies Demonstrate Multigenetic Origins of Congenital Heart Disease
Kryn Stankunas, Ching Shang, Karen Y. Twu, Shih-Chu Kao, Nancy A. Jenkins, Neal G. Copeland, Mrinmoy Sanyal, Licia Selleri, Michael L. Cleary, Ching-Pin Chang Circ Res. Author manuscript; available in PMC 2009 Sep 26. Published in final edited form as: Circ Res. 2008 Sep 26; 103(7): 702–709. Published online 2008 Aug 21. doi: 10.1161/CIRCRESAHA.108.175489 PMCID: PMC2633052

Pbx1/Pbx2 govern axial skeletal development by controlling Polycomb and Hox in mesoderm and Pax1/Pax9 in sclerotome
Terence D. Capellini, Rediet Zewdu, Giuseppina Di Giacomo, Stefania Asciutti, Jamie E. Kugler, Anna Di Gregorio, Licia Selleri Dev Biol. Author manuscript; available in PMC 2018 Apr 26.Published in final edited form as: Dev Biol. 2008 Sep 15; 321(2): 500–514. Published online 2008 Apr 16. doi: 10.1016/j.ydbio.2008.04.005 PMCID: PMC5918304

Interleukin-10 Expression in Macrophages during Phagocytosis of Apoptotic Cells Is Mediated by the TALE homeoproteins Pbx-1 and Prep-1
Elaine Y. Chung, Jianguo Liu, Yoichiro Homma, Yunhua Zhang, Andrea Brendolan, Matilde Saggese, Jihong Han, Roy Silverstein, Licia Selleri, Xiaojing Ma. Immunity 2007 Dec 21; 27(6): 952–964. doi: 10.1016/j.immuni.2007.11.014 PMCID: PMC2194654

B-cell development fails in the absence of the Pbx1 proto-oncogene
Mrinmoy Sanyal, James W. Tung, Holger Karsunky, Hong Zeng, Licia Selleri, Irving L. Weissman, Leonore A. Herzenberg, Michael L. Cleary Blood. 2007 May 15; 109(10): 4191–4199. Prepublished online 2007 Jan 23. doi: 10.1182/blood-2006-10-054213 PMCID: PMC1885499

Cooperation between p27 and p107 during Endochondral Ossification Suggests a Genetic Pathway Controlled by p27 and p130
Nancy Yeh, Jeffrey P. Miller, Tripti Gaur, Terence D. Capellini, Janko Nikolich-Zugich, Carmen de la Hoz, Licia Selleri, Timothy G. Bromage, Andre J. van Wijnen, Gary S. Stein, Jane B. Lian, Anxo Vidal, Andrew Koff Mol Cell Biol. 2007 Jul; 27(14): 5161–5171. Published online 2007 May 14. doi: 10.1128/MCB.02431-06 PMCID: PMC1951950

Hypomorphic Mutation of the TALE Gene Prep1 (pKnox1) Causes a Major Reduction of Pbx and Meis Proteins and a Pleiotropic Embryonic Phenotype
Elisabetta Ferretti, J. Carlos Villaescusa, Patrizia Di Rosa, Luis C. Fernandez-Diaz, Elena Longobardi, Roberta Mazzieri, Annarita Miccio, Nicola Micali, Licia Selleri, Giuliana Ferrari, Francesco Blasi Mol Cell Biol. 2006 Aug; 26(15): 5650–5662. doi: 10.1128/MCB.00313-06 PMCID: PMC1592771

Pbx1/Pbx2 requirement for distal limb patterning is mediated by the hierarchical control of Hox gene spatial distribution and Shh expression.
Capellini TD, Di Giacomo G, Salsi V, Brendolan A, Ferretti E, Srivastava D, Zappavigna V, Selleri L. Development. 2006 Jun;133(11):2263-73. doi: 10.1242/dev.02395. Epub 2006 May 3. PMID: 16672333.

A Pbx1-dependent genetic and transcriptional network regulates spleen ontogeny.
Brendolan A, Ferretti E, Salsi V, Moses K, Quaggin S, Blasi F, Cleary ML, Selleri L. Development. 2005 Jul;132(13):3113-26. doi: 10.1242/dev.01884.

Pbx3 Deficiency Results in Central Hypoventilation
Joon Whan Rhee, Akiko Arata, Licia Selleri, Yakop Jacobs, Satoru Arata, Hiroshi Onimaru, Michael L. Cleary Am J Pathol. 2004 Oct; 165(4): 1343–1350. doi: 10.1016/S0002-9440(10)63392-5 PMCID: PMC1618620

The TALE Homeodomain Protein Pbx2 Is Not Essential for Development and Long-Term Survival
Licia Selleri, Jorge DiMartino, Jan van Deursen, Andrea Brendolan, Mrinmoy Sanyal, Elles Boon, Terence Capellini, Kevin S. Smith, Joon Rhee, Heike Pöpperl, Gerard Grosveld, Michael L. Cleary Mol Cell Biol. 2004 Jun; 24(12): 5324–5331. doi: 10.1128/MCB.24.12.5324-5331.2004 PMCID: PMC419882

Requirement for Pbx1 in skeletal patterning and programming chondrocyte proliferation and differentiation
L Selleri M J Depew, S K Chanda, K Y Tsang, K S Cheah J L Rubenstein, S O'Gorman, M L Cleary. Development 2001 Sep;128(18):3543-57. doi: 10.1242/dev.128.18.3543.

A novel zinc finger gene on human chromosome 1qter that is alternatively spliced in human tissues and cell lines.
M Saleh, L Selleri, G A Evans Am J Hum Genet. 1993 Jan; 52(1): 192–203. PMCID: PMC1682137

Interphase cytogenetics for the detection of the t(11;22)(q24;q12) in small round cell tumors.
M Giovannini, L Selleri, J A Biegel, K Scotlandi, B S Emanuel, G A Evans J Clin Invest. 1992 Nov; 90(5): 1911–1918. doi: 10.1172/JCI116068 PMCID: PMC443252

Molecular localization of the t(11;22)(q24;q12) translocation of Ewing sarcoma by chromosomal in situ suppression hybridization.
L Selleri, G G Hermanson, J H Eubanks, K A Lewis, G A Evans Proc Natl Acad Sci U S A. 1991 Feb 1; 88(3): 887–891. doi: 10.1073/pnas.88.3.887 PMCID: PMC50919

Prognostic significance of "short-term" effects of chemotherapy on MYC and histone H3 mRNA levels in acute leukemia patients.
D Venturelli, B Lange, F Narni, L Selleri, M T Mariano, U Torelli, A M Gewirtz, B Calabretta Proc Natl Acad Sci U S A. 1988 May; 85(10): 3590–3594. doi: 10.1073/pnas.85.10.3590 PMCID: PMC280259

Activation of c-myb expression by phytohemagglutinin stimulation in normal human T lymphocytes.
G Torelli, L Selleri, A Donelli, S Ferrari, G Emilia, D Venturelli, L Moretti, U Torelli Mol Cell Biol. 1985 Oct; 5(10): 2874–2877. doi: 10.1128/mcb.5.10.2874 PMCID: PMC367031